The Summit Programme Committee invited Human Brain Project members, collaborators and researchers interested in open neuroscience, to submit high quality abstracts to the Human Brain Project Summit 2023.

The evaluation of the submitted abstracts was strictly based on scientific content and infrastructure relevance. Among the abstracts that were submitted, the Evaluation Committee identified the best abstracts in the following categories:

(I) Best Abstract Award on Neuroscientific and Medical Research

  • “Simulating the emergence of conscious and unconscious states at the whole-brain level (Showcase 3)” will be presented by Maria Sacha (CNRS – Universite Paris-Saclay) during the Best Abstract Award session, as well as poster #169

(II) Best Abstract Award on Methodical Developments and Technology

  • “VoluBA: Interactive registration of high-resolution volumes to 3D reference atlases” will be presented by Julia Thönnißen (Forschungszentrum Jülich GmbH) during the Best Abstract Award session, as well as a poster #52
  • “Pioneering open neuroscience – the role of the curation services” will be presented by Sophia Pieschnik (University of Oslo) during the Best Abstract Award session, as well as a poster #26


  • Best Abstract Awards: Monday, 28 March, from 16:00-16:30
  • Poster & Networking session: Wednesday, 29 March 2023, from 15:45 – 18:30
  • Poster & Networking session: Thursday, 30 March 2023, from 15:45 – 18:30


  1. openMINDS SANDS – a metadata model for ontology-based brain atlas definitions in graph databases
  2. TVBase: Utilizing Computational Semantics to Map Biomedical Knowledge onto the Brain
  3. EBRAINS datasets reveal region, sex and age differences in dopamine receptor cell densities in the mouse forebrain
  4. Efferent connections of the orbitofrontal, posterior parietal and insular cortices in the rat
  5. Changes in synaptic dynamics underlies benzodiazepine resistance in paediatric status epilepticus
  6. Topographic variation in neurotransmitter receptor densities explain differences in intracranial EEG spectra
  7. The Brain Scaffold Builder: a component framework for large multiscale brain models and rapid prototyping
  8. Analyzing thalamocortical tract-tracing experiments in a common reference space
  9. Showcase 1 – the virtual aging brain: structure-function relationship and cognitive decline
  10. Bayesian inference on virtual brain models to reveal the causal mechanisms of disorders
  11. Inferring the micro-circuitry of mere presence
  12. Data-driven signaling pathway modelling
  13. Neural correlates of predictions and prediction errors during multisensory object discrimination in the rat somatosensory barrel cortex
  14. Decorrelation as a principle for the emerging of Structured Flows on Manifolds
  15. Generating High Performance Simulations from a Portable Data Format using Arbor
  16. State-dependent brain responsiveness at the level of local circuits and mesoscale (part A Live Paper T2.5)
  17. State-dependent brain responsiveness: from meso to macroscale level (part B Live Paper T2.5)
  18. Multiscale sinusoidal perturbation of slow cortical spontaneous dynamics
  19. Multiscale dynamical characterization of spontaneous cortical brain states: from synchrony to asynchrony
  20. Showcase #1 – Modelling regional variance
  21. Exploring the coupling between electrophysiology and hemodynamics during slow wave activity in the neocortex
  22. AKAP79 enables calcineurin to directly suppress protein kinase A
  23. Variability of Reaching Trajectories in Hand Space and Joint Space
  24. Structuring cortical wave analysis with Cobrawap: a modular and adaptable pipeline for heterogeneous datasets
  25. Tracking the pre-processing and analysis of electrophysiological data with Elephant and Alpaca
  26. Pioneering open neuroscience – the role of the curation services
  27. Building Responsible Data Governance into EBRAINS
  28. Formal and Informal Infrastructures of Collaboration in the Human Brain Project
  29. KnowledgeSpace: a global portal for discovering and integrating FAIR data from around the world
  30. Data Movement to Facilitate Scientific Workflows in the Fenix Research Infrastructure
  31. Garment EEG: a novel textile system to monitor electroencephalographic activity
  32. Automatic and manual prediction of epileptic seizures based on ECG
  33. Quantitative Susceptibility Mapping and χ-separation method: how MRI can help us understand COVID-19
  34. The Virtual Brain Ontology – Towards a Semantic Web for Brain Simulation
  35. Small changes in brain state affect the global cortical functional networks and how sensory inputs are processed
  36. Interactively exploring metadata with Beaverdam
  37. MATLAB user interface for openMINDS metadata registration
  38. Hessian-driven spine neck tracing boosts SENPAI segmentation on super-resolution microscopy images
  39. Advanced magnetic resonance imaging to study brain alterations in people infected with SARS-COV-2
  40. Investigating cross-modal contextual effects in human somatosensory cortex with laminar fMRI
  41. openMINDS extensions for in-depth graph database descriptions of electrophysiology experiments
  42. Enhanced simulations of whole-brain dynamics using hybrid resting-state structural connectomes
  43. Multiscale Modelling of the Cerebellum: structure-dynamics-function
  44. Mouse cerebellum reconstruction: declive model with structural and functional regional specificity
  45. A semi-automated pipeline for cell detection and white matter segmentation in the macaque brain
  46. Online workflows for analysing murine brain images
  47. DeepSlice: Atlas registration of mouse and rat brain sections with deep learning.
  48. Reconstructing axonal arborizations from sectioned mouse brains through alignment and stitching.
  49. Where structure meets function: human brain connectivity from dMRI and intracerebral electrical stimulation
  50. Nested parcellations connectome delivered for one large dataset using Constellation algorithm
  51. Multi-scale multi-modal connectomic and cytoarchitectonic mapping in the same human brain section
  52. VoluBA: Interactive registration of high-resolution volumes to 3D reference atlases
  53. Linking the multilevel human brain atlas to neuroscience workflows with siibra
  54. A conceptual framework for positioning and integrating brain data in murine 3D brain atlases
  55. Interactive brain image segmentation with webilastik
  56. High-throughput method for brain-wide characterisation of genetically diverse AD mice
  57. Cytoarchitectonic Maps of Five New Areas in the Human Dorsolateral Prefrontal Cortex
  58. The Waxholm Space rat brain atlas v4 – a 3D atlas for efficient analysis and transparent reporting
  59. Accelerated inference on fields: virtual brains in JAX.
  60. Model driven data analysis on the Human Intracereberal Platform: a Virtual Brain app
  61. Co-simulation workflow for brain simulations: a multi-scale mouse brain model with TVB and NEST
  62. A Computational Approach To Investigate Parkinson’s Disease Bradykinesia in Reaching Movements
  63. Learning Sensorimotor-Predictions through Mismatch-Based Hebbian Plasticity
  64. Emergence of oscillations in a biologically realistic model of a V1 cortical column
  65. Computational modelling of the pathway between dopamine receptors and Ca2+ channels in layer II stellate cells
  66. Bio-Inspired Backpropagation in Spiking Neural Networks
  67. Gradient free optimization of neuroscience models at different scales with L2L
  68. A layered cognitive architecture for motivational control in a navigation task
  69. The virtual multiple sclerosis patient: on the clinical-radiological paradox
  70. Modelling spatio-temporal dynamics of interictal spikes
  71. The structured flow on the brain’s resting state manifold
  72. A multi-layer mean-field model of the cerebellar cortex can faithfully account circuit microscopic properties
  73. Efficient Bayesian Inference for Virtual Brain Modeling: Incorporating Prior Information and automatic Algorithms for Disorder Prediction
  74. Characterization of regional differences in resting-state fMRI with a network model of brain dynamics
  75. Tuning to resonances: Homeostatic plasticity in the Olivocerebellar system
  76. A generative model for continual learning based on self-organizing maps.
  77. Fitting finite-size population models to networks of leaky integrate-and-fire neurons
  78. Decreased brain responsiveness to multimodal sensory stimulations during absence seizures in awake rats
  79. A fluid hierarchy in multisensory integration properties of large-scale brain networks
  80. SpiNNaker 2 Enables Multi-Scale Spiking Neural Network Simulation
  81. The human multiscale brain connectome
  82. A computational model of Alzheimer reproduces features of disease severity in EEG recordings
  83. Simulating [18]FDG-PET based on a neurogliovascular ATP model in The Virtual Brain
  84. Concepts for reproducible network connectivity
  85. Inferring the mechanisms of resting-state network reconfiguration upon focal region silencing
  86. Simulating deep brain stimulation using a multiscale model in The Virtual Brain
  87. The Arbor Simulator: growing a sustainable, portable, and performant ecosystem
  88. A biologically plausible decision-making model of interacting cortical columns
  89. Cholinergic neuromodulation of cortical brain states: an experimental and computational study of cellular and network mechanisms
  90. TheVirtualBrain in the Neurorobotics Platform: Haken-Kelso-Bunz bimanual coordination
  91. The Modular Science Framework: Deployment, Orchestration and Monitoring of Coupled Brain Simulations
  92. Cross-comparison of morphologically detailed simulators on modern CPUs and GPUs using the Brain Scaffold Builder
  93. Bridging high-level neural modelling languages and accelerated neural simulation engines
  94. Modernisation of NEURON Simulator toolchain and Deployment on EBRAINS Platforms
  95. NEST-SONATA: Fast parallel instantiation of explicitly specified large-scale neuronal network models
  96. Enabling Multiscale In-Transit Processing Through Insite Pipeline
  97. Brain stimulation effects on seizure dynamics through whole brain modeling for drug-resistant epilepsy
  98. Personalized whole brain network modelling on virtual epilepsy surgery
  99. A Simulation Based Fractal Feature Paradigm for capturing evolution of Interictal activities
  100. Multiscale Co-Simulation of TheVirtualBrain with NEST, ANNachy and NetPyNE (NEURON) spiking networks
  101. Latest developments in the electrical model building toolset
  102. Interplay between synaptic scaling and structural plasticity maintains the robust firing rate homeostasis
  103. Virtual brain simulations reveal subject-specific excitatory/inhibitory profiles of dementia patients
  104. Large-scale brain signatures of fluid dynamics and responsiveness linked to consciousness
  105. Now you see it more – Multiscale visualization on EBRAINS
  106. Building detailed neuron models from patch-clamp and MEA data using the BluePyOpt and LFPy libraries
  107. BRAVE: protecting the brain from COVID-19 mediated neurodegeneration through inflammasome inhibition
  108. Modelling reentry excitation and interventions in a personalized cortical model of epilepsy
  109. Computation of Protein-Protein Interaction Kinetics using τ-RAMD
  110. Simulation of a Biophysical Morphological Realistic Model of the Inferior Olivary Nucleus in Arbor
  111. Hippocampal learning in Alzheimer’s disease: integrating experimental data and computational modeling
  112. Modeling and simulating spiking neurons and synaptic plasticity with NESTML
  113. Creating realistic networks in silico of health and disease using the Snudda software
  114. Mean-field approximation of biophysical neuronal network to capture healthy & pathological dynamics
  115. Computational modeling of neuron-astrocyte interactions using the NEST simulator (AstroNeuronNets)
  116. Interaction schemes and spatial organization of cells in computational models of neuron-astrocyte networks
  117. A neuro-glia model to link mean-field models to the BOLD signal
  118. Converging evidence of impaired brain function in systemic lupus erythematosus: changes in perfusion dynamics and intrinsic functional connectivity
  119. Learning heterogeneous delays of spiking neurons for motion detection
  120. Recurrent neural networks for multiscale object-based attention during contour grouping
  121. An ANN family for systematic analysis of receptive field size and computational depth in the primate visual hierarchy
  122. Object-based perception and action
  123. Neuromorphic 3D Perception with GeNN
  124. DeepThickness: A Deep Learning Method for Brain MRI Cortical Thickness Estimation
  125. 7T MRI prediction from 3T MRI data: application to the IMAGEN cohort.
  126. A simulating and assimilating platform for the whole human brain with applications
  127. A nonparametric tool to quantify the content of information transmitted between neural populations
  128. Multidisciplinary and multiscale perspective on cortical feedback mechanisms
  129. Loss shaping enhances learning with EventProp in spiking neural networks
  130. Control of slow oscillations and epileptiform discharges by photoswitchable M1 muscarinic ligands
  131. Dynamics of ictogenic and irritative zones using machine learning of interictal epileptiform discharges
  132. Selectively branched higher-order thalamocortical axons underlie functional forebrain subnetworks
  133. Multimodal Brain-Phenotype Relations of the Angular Gyrus: Group Trends versus Individual Profiles
  134. Mediation Analysis of neural Response’s Shape
  135. Lifestyle- & body-related differences in neurite morphology of white matter tracts in older adults
  136. Cortico-subcortical interaction and dynamical state switching in the resting brain
  137. Linking hubs, embryonic neurogenesis, transcriptomics and diseases in human brain networks
  138. Fiber enhancement and 3D orientation analysis in volume fluorescence microscopy
  139. Closed-loop brain-inspired meta-reinforcement learning rules during cognitive inhibition control
  140. On-chip spike coding control: Linear-quadratic-Gaussian filtering through sparse and irregular spiking
  141. Neurophysiology of gaze visual orientation: a synthesis of the contribution of animal studies
  142. All-optical method to study cortical information integration in awake and anesthetized mice
  143. Biologically plausible gated recurrent neural networks for working memory and learning-to-learn
  144. Functional network complexity reflects diverse reward contexts in macaque premotor cortex
  145. Moth trajectories recorded with a lab-on-cables exhibit a Lévy flight pattern
  146. Digital twin for upper limb closed-loop brain computer interface and exoskeleton neurorehabilitation
  147. Enhancing Neuroscience Research with Intuitive GUI Widgets in EBRAINS lab
  148. Bringing the Analysis Workflow for 3D-PLI Data with Oblique Measurements to HPC
  149. Synaptic proteome database and Bioconductor tools Synaptome.db and BioNAR to facilitate building and analysis of customised synaptic PPI networks.
  150. Estimating brain connectome for modeling deep brain stimulation effect in Parkinson’s disease
  151. Normalizing the brain connectome for communication through synchronization
  152. Frites: a Python package for functional connectivity analysis and group-level statistics of neurophysiological data
  153. Task T1.12 (WP1): Data-driven and model-based workflows for inference and validation of task-related brain network models
  154. SpecSeg: cross-spectral power based segmentation of neurons in chronic calcium imaging datasets
  155. Layer-specific plasticity of feedforward and contextual neuronal populations in mouse visual cortex
  156. Data-driven analysis of brain’s resting-state manifold
  157. Characterizing thalamic sodium accumulation in focal epilepsy to better inform patients’ modelling
  158. Multiscale responsiveness following microstimulation of the prefrontal and parietal cortices in wakefulness and anaesthesia
  159. Identification and neuromodulation of consciousness states: experimental and clinical considerations
  160. Circuit and network dynamics of the human cerebral cortex in vitro
  161. The Virtual Basal Ganglia
  162. The “motor-way” to decision-making: the role of premotor oscillatory activity in cue-guided choice
  163. Neural Mechanism of Cue-triggered Decision-making: the Role of the Motor System
  164. Looking at previous cue sites reactivates value coding for serial evaluation in orbitofrontal cortex
  165. A multisensory profile protocol: spatial and postural virtual reality subsets applied to vestibular disorders
  166. Role of the Motor Cortex and Social Environment in Cue-Triggered Decision-Making: Insights from Single-Pulse TMS and Action Observation
  167. Laminar feedback signals in visual cortex related to an anticipated future during navigation
  168. Laminar dynamics in the awakening sensory cortex
  169. Simulating the emergence of conscious and unconscious states at the whole-brain level (Showcase 3)
  170. Apparent divergence of EEG signal diversity and integrated information in rats during anesthesia
  171. Experimentation, Learning and Dialogue: a novel approach to dual use of concern in brain research
  172. The EBRAINS Italian national node: multiscale, multimodal and multimodel approach for integrated services.
  173. EBRAINS Spanish Node